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Drug Discovery

PARPs as cancer drug targets – first EC-approved drug

Drug Discovery

Microtubule destabilization by suprafenacine: Template for novel anti-cancer drugs

ADME-Tox, Drug Discovery

Predicting CYP induction in stable cell lines

ADME-Tox, Drug Discovery, Headlines, Supplying Discovery Tools

Biomimetic Chemistry, a new route for metabolite synthesis

Drug Discovery, Supplying Discovery Tools

Immunotherapy Screening – CD137:CD137L pathway

Cell Sourcing - Cell Culture Technologies, Drug Discovery, Supplying Discovery Tools

Characterization & Applications of Human Cardiomyocytes

Drug Discovery

Immunotherapy Screening – CD40:CD40L pathway

Cell Biology and Signalling, Drug Discovery

Fluorescent ShK toxin for Kv1.3 ion channels

Activators, inhibitors and small molecules screening and enzyme profiling
Drug Discovery

Immunotherapy Screening – GITR:GITRL pathway

Drug Discovery

Where can I find the best PARPs?

Drug Discovery

MMP-25 activity assay – the first one on the market!

Drug Discovery

EnSens, or how to overcome FRET assay limitations

Cell Biology and Signalling, Drug Discovery

Epigenetics Writers – Readers – Erasers: Targeting Readers in Drug Discovery

Drug Discovery

8 new JARID1 – JMJD2 HMT assays

Cell Biology and Signalling, Drug Discovery

Writing – Erasing – Reading Epigenetics: Targeting Erasers in Drug Discovery

Drug Discovery

15 Ubiquitin – Proteasome inhibitors for cancer research

Drug Discovery

alpha-GalCer analog, 7DW8-5 – a potential adjuvant in Cancer Immunotherapy?

Cell Biology and Signalling, Cell Sourcing - Cell Culture Technologies, Drug Discovery, Headlines, Supplying Discovery Tools

Get 1.8 fold more cardiomyocytes with MesoFate medium

Activators, inhibitors and small molecules screening and enzyme profiling
Drug Discovery

Where to buy Topo inhibitors and analogs?

Drug Discovery

H3K4me3 Histone Demethylase Fbxl10 Activity Assay

Drug Discovery

Epigenetics Writers – Readers – Erasers: Targeting Writers in Drug Discovery

Drug Discovery, News

Proteasome inhibitor approved by FDA for Myeloma retreatment

Drug Discovery

Immunotherapy – BLTA:HVEM, CD47:SIRPα in drug discovery

Nucleosome schematic structure
Drug Discovery, Gene Expression - Molecular Biology

5 new research tools to perform chromatin and epigenetic analysis

Drug Discovery

Immunotherapy Screening – A focus on PD-1/PD-L1/PD-L2 Pathway in drug discovery

Drug Discovery

Immunotherapy Screening – B7-1 / CD28 and B7-1 / CTLA4 Pathways in Drug Discovery

Drug Discovery, Supplying Discovery Tools

How to measure Calcium in cell based assays?

ADME-Tox, Cell Sourcing - Cell Culture Technologies, Drug Discovery

Plateable Hepatocytes… the "one cell type doesn't fit all" syndrome

Cell Sourcing - Cell Culture Technologies, Drug Discovery, Headlines, Supplying Discovery Tools

Isogenic Knockout iPSC Lines for Modeling of CNS Disorders

Activators, inhibitors and small molecules screening and enzyme profiling
Drug Discovery

Mutant or wild-type: 7 effective means to screen and profile Human EZH2 Methyltransferase

Primary cells, active enzymes and small molecules for stem cell and Drug discovery research
Drug Discovery, Supplying Discovery Tools

Return of SIRT1 deacetylase – Why is SIRT1 so attractive in Drug discovery and Stem cell research?

Immunocytochemical staining of stable BRCA1 KD SilenciX cell line
Cell Sourcing - Cell Culture Technologies, Drug Discovery

PARP inhibitors are less synthetically lethal in hypoxic conditions – AACR 2014

Drug Discovery, Supplying Discovery Tools

Bioactive small molecule sourcing – when quality meets expectations

Cell Biology and Signalling, Drug Discovery, Headlines, Supplying Discovery Tools

A 96-well Invasion Assay Compatible with High Content Screening

EpiGold™ Histone Peptide Array Data-ECL
Drug Discovery

Histone Peptide Arrays' contribution in Epigenetic studies

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