Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
Page 24 - Metabolism
Article
3 novel PD-L1 post-translational modifications identified
April 18, 2017
In a recent paper, Horita H. et al. identified a set of novel Post-Translational Modifications (PTMs) of the protein Programmed Cell Death Ligand (PD-L1).
Article
3D Cell culture: Innovative cell culture devices for more predictive 3D models
April 05, 2017
One of the biggest challenges as a researcher in life sciences, is to obtain proof of concept the more predictive as possible. To help you to reach your objectives, many innovative tools are being developed
Article
Stauprimide inhibits c-myc transcription in cancer cells
April 04, 2017
Stauprimide is known to prime Embryonic Stem Cells (ESC) by targeting the c-Myc-activating transcription factor NME2. Its mechanism of action is linked to the inhibition of the nuclear localization of
Article
Fluorescence microscopy: how to improve your Live Cell Imaging
March 09, 2017
For more than 2 years now, the Silicon Rhodamine-like (SiR) technology has allowed the live cell imaging field with fluorescence microscopy to evolve significantly.
Fluorescent SiR-probes have appeared
Article
How to combine advantages of ELISAs and Arrays - Target validation with Quantibody®
March 02, 2017
On your journey to Biomarker profiling, you will reach the point where you need to quantify the proteins of interest identified along the way (eg. validation of semi-quantitative array results; biomarker
Article
New, more sensitive monoclonal based Allopregnanolone kit for AD research
February 20, 2017
Progesterone derived Allopregnanolone (ALLO) is an extensively studied neurosteroid that has been shown to be involved in neurodegenerative diseases, including Alzheimer's, Parkinson's disease, and multiple
Application Note
New - Continued use immunotherapy cell line expressing recombinant PD-1
February 03, 2017
PD-1/NFAT-Luciferase reporter jurkat cell line used to monitor the T cell response inhibition via PD-1 interacting with PD-L1/PD-L2
PD-1 / NFAT Reporter - Jurkat Cell Line
The PD-1 reporter cell line is
Article
How to choose the perfect buffer to get a pure, stabilised, functional protein
January 30, 2017
Protein biochemistry brings together a vast and varied world of methods of protein production, purification and characterization. Once you have successfully achieved the production of your protein in a
Article
New effective anti-Human IFN neutralizing antibody
January 13, 2017
Neutralizing MAb Anti-Human Interferon Lambda Receptor 1, Clone MMHLR-1 - PBL Assay Sciences at tebu-bio
PBL Assay Sciences offer a new monoclonal antibody to neutralize Human Interferon (IFN) activity,
