Assays & Kits

Glutamate Decarboxylase (GAD) is the rate-limiting enzyme that converts glutamate into the inhibitory neurotransmitter γ-aminobutyric acid (GABA), a potent inhibitory neurotransmitter in the central nervous system, It can reduce blood pressure, promote brain vitality, nourish nerve cells, maintain neurostability, promote growth hormone secretion, protect liver and benefit kidney, and so on. At present, it has been widely used in medicine and health food. CheKine™ Micro Glutamate Decarboxylase (GAD) Activity Assay Kit can be used to detect biological samples such as animal tissue, serum or plasma. In this kit, GAD catalysed glutamate to produce GABA, and the berthelot reaction was used to measure GABA content and thus GAD activity.

γ-Aminobutyric Acid (GABA) is a non-proteinogenic amino acid consisting of four carbon atoms, which is widely present in the organisms of plants, animals, and microorganisms. Within plants, GABA is primarily generated through decarboxylation of L-glutamate catalyzed by glutamate decarboxylase. In the mammalian brain, GABA serves as an efficacious inhibitory neurotransmitter, exhibiting functions such as lowering blood pressure, enhancing brain vitality, nourishing nerve cells, maintaining neural stability, promoting growth hormone secretion, and benefiting liver and kidney health. It has already found extensive applications in both pharmaceuticals and health food products.Principle of Determination: GABA reacts with phenol and sodium hypochlorite, giving rise to a blue-green product that exhibits a maximum absorbance at 640 nm.

*Easy to analyze the autophagy pathway just by adding the reagent *All-in-one Kit with Lysosome Acidification Inhibitor

Sandwich TR-FRET immunoassay for the quantitative measurement of human CCL17 (C-C motif chemokine 17; CC chemokine TARC) in cell culture supernatants. The kit does not include a recombinant human CCL17/TARC standard, which must be purchased separately from R&D Systems® (catalog number 364-DN).

Sandwich TR-FRET immunoassay for the quantitative measurement of human CCL17 (C-C motif chemokine 17; CC chemokine TARC) in cell culture supernatants. The kit does not include a recombinant human CCL17/TARC standard, which must be purchased separately from R&D Systems® (catalog number 364-DN).

Sandwich TR-FRET immunoassay for the quantitative measurement of human CCL17 (C-C motif chemokine 17; CC chemokine TARC) in cell culture supernatants. The kit does not include a recombinant human CCL17/TARC standard, which must be purchased separately from R&D Systems® (catalog number 364-DN).

Sandwich TR-FRET immunoassay for the quantitative measurement of human CCL17 (C-C motif chemokine 17; CC chemokine TARC) in cell culture supernatants. The kit does not include a recombinant human CCL17/TARC standard, which must be purchased separately from R&D Systems® (catalog number 364-DN).

DR3 (death receptor 3), also known as tumor necrosis factor receptor superfamily member 25 or TNFRSF25, is a membrane receptor of the tumor necrosis factor receptor superfamily of proteins (TNFRSF), which associates with TL1A (TNF-like protein 1A) in T and NK cells. DR3 has been recognized as a significant anti-apoptotic and differentiation factor and it is a co-stimulatory receptor. TL1A, also called TNFSF15, is a member of the tumor necrosis factor family. It is expressed in different immune cells, such as monocyte, macrophage, dendritic cell, T cell and non-immune cells. TL1A competitively binds to DR3, having a higher affinity for DcR3 (decoy receptor 3), providing stimulatory signal for downstream signaling pathways. It then regulates proliferation, activation, apoptosis, and chemokine production in effector cells. The role of DR3 in T cell activation, and consequently in cytokine secretion and cell proliferation, makes it an attractive target in cancer therapy. Inhibition of DR3-

DR3 (death receptor 3), also known as tumor necrosis factor receptor superfamily member 25 or TNFRSF25, is a membrane receptor of the tumor necrosis factor receptor superfamily of proteins (TNFRSF), which associates with TL1A (TNF-like protein 1A) in T and NK cells. DR3 has been recognized as a significant anti-apoptotic and differentiation factor and it is a co-stimulatory receptor. TL1A, also called TNFSF15, is a member of the tumor necrosis factor family. It is expressed in different immune cells, such as monocyte, macrophage, dendritic cell, T cell and non-immune cells. TL1A competitively binds to DR3, having a higher affinity for DcR3 (decoy receptor 3), providing stimulatory signal for downstream signaling pathways. It then regulates proliferation, activation, apoptosis, and chemokine production in effector cells. The role of DR3 in T cell activation, and consequently in cytokine secretion and cell proliferation, makes it an attractive target in cancer therapy. Inhibition of DR3-