Results for Peptides & Amino Acids ( 10701 )
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SYFPEITHI MHC binding peptide SB-PEPTIDE offers SYFPEITHI peptide for immune reactivity studies and MHC ligand assays. Major Histocompatibility Complex (MHC) MHC is a large cluster of genes, called Human Leukocyte Antigens (HLA) in humans and H-2 complex in mice. This DNA locus of highly polymorphic genes codes for MHC molecules, present on the cell surface, whose function is to present antigens to T-cells. Foreign antigen presentation by MHC proteins triggers the appropriate T-cells to proliferate and generate a specific cellular immune response. The polygenism and polymorphism of MHC molecules make it difficult for pathogens to evade immune responses. This complex contains several different MHC class I and MHC class II genes to ensure that each individual has a unique set of MHC molecules capable of binding to a diverse range of peptides. MHC-I proteins are found on all nucleated cells, while MHC-II molecules are restricted to antigen-presenting cells (APCs). MHC bindi