Page 32 - ADME/Tox

SUMO-tag gene fusion acts as both a chaperonin and as an initiator of protein folding in both prokaryotic and eukaryotic systems. Addition of this tag enables protein experts to increase the expression

Statins are HMG-CoA reductase inhibitors, well-known  medications for treating Hypercholesterolemia. Simvastatin is a member of this "Statin family" and controls

A recent publication by Torres et al. has found that B7-1/CD80, EG-VEGF/PK1, IL-29, NRG1-beta1/HR

Which roles do IDO and TDO play in Immunotherapy? Immune evasion is one of the identifying hallmarks of cancer and researchers are investigating the complex mechanisms that enable cancer

Histon Deactetylases (HDACs) are overexpressed and show very high activities in a number of tumor cells. Expression of HDAC1, -5, and -7 can be even

A publication earlier this year by Bárcena et al. shows that angiogenin plays a crucial role in the onset and development of liver

In this post, I invite you to discover some state-of-the art methods to measure the activation of the most prominent small G proteins.

In their most recent publication

Pharmaceutical, biotech and medical device industries apply restrictive quality systems in their bio-production processes. Among the numerous parameters controlled daily by scientists, I have selected

For secretome biomarker profiling, several solutions, including arrays allowing to screen up to 1,000 factors, have been available for some time now. These profiling solutions, however,

For one year now,  SiR-Actin and SiR-Tubulin, the second generation of tools to stain actin and tubulin in