Page 44 - Scientific Library
Profiling of secretome biomarkers - pancreatic cancer
Following a post on tools for discovery of secretome biomarkers in biological samples, a recent publication by Torres et al. depicts how some of these tools (i.e. antibody arrays)
Where to buy Topo inhibitors and analogs?
DNA topoisomerase I and DNA topoisomerase II (Topo I and Topo II) are nuclear enzymes which regulate the topological state of the DNA helix by transiently breaking and rejoining DNA strands. They also
Tips for Optimizing Cell Culture Conditions with Hydrogels
In a previous post on Cellular Matrices for Translational Research, I introduced HyStem hydrogels. In order to engineer
How to probe motor-domains of kinesins?
In the past, molecular motor proteins like kinesins have been investigated with macromolecular approaches. Recent research on kinesins has been focused on resolving how kinesin is regulated by intramolecular
Tumour microenvironment - glioblastoma
Factors released by tumour cells can have an impact on the outcome of cancer in a patient, and they can be used as diagnostic or prognostic biomarkers. A deeper study on the tumour microenviroment (TME)
Functional Proteomics for biomarker characterisation
Sircol for soluble and insoluble collagen assays!
Measuring soluble collagen in biological samples is a straightforward experiment which can be done with the Sircol
Choose your complement!
The complement system helps the ability of antibodies and phagocytic cells to clear pathogens from an organism. It is part of the innate immune system that is not adaptable and does not change over the
Growth factors in cartilage biology and osteoarthritis
Cartilage is a flexible connective tissue which can rapidly grow and which is specialized to absorb and resist compression. The perichondrium, a vascularized layer, surrounds the tissue which does not
Activation of RhoA, Rac1 and Cdc42 - New G-LISA Trial kits
Small GTP-binding proteins such as RhoA, Rac1, and Cdc42 are involved in regulating cell signalling pathways and impact a wide range of cellular processes, functions, and morphology. They bind and hydrolyze