Page 33 - Cell & Gene Therapy

For one year now,  SiR-Actin and SiR-Tubulin, the second generation of tools to stain actin and tubulin in

The role of STAT3 signaling in the activity of dendritic cells (DC) has been recently revealed in a publication by Okada et al.

G Protein Coupled Receptors (GPCR) and ion channels are important targets in drug development. Both target classes represent membrane proteins which require convenient and robust cell-based assays for

Ion channels play an important role in perception and transmission of pain sensations. Furthermore, dysfunctions of certain ion channels are involved in neuronal disorders, such as epilepsy, Alzheimer's

In a recent post on  Venomous toxin ion channel modulators, we looked at toxin derived peptides to manipulate a wide variety of ion channels. These toxins can be used as tools to characterize

Isolation of highly purified untagged proteins is crucial in today's R&D programs. Up to now, recombinant protein production approaches were often based on the use of "tags" to make protein purification

A recent article by E. Langer

The determination of serum blood urea nitrogen (BUN) is currently the most widely used screening test for the evaluation of kidney function. The test is frequently run along with the serum creatinine test,

Microtubules are key components of the cytoskeletal structure of eukaryotic cells.

CRISPR/Cas9 is relatively simple to

Ion channels are proteins with pore-forming abilities. Their selective capabilities to let ions cross the cell membrane involves them in crucial cellular functions (controlling membrance potential, the

We have been closely following the interesting case of the discontinuation of tobacco acid pyrophosphatase (TAP) and the efforts of the world's RNA biologists to find a suitable alternative. Our previous