Compound Libraries

A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS;

A unique collection of 105 beta-lactam compounds, can be used in HTS and HCS;

A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS.

A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.

The library consists of more than 4,000 members belonging 22 scaffolds (average 180 compounds per scaffold).

Targetmol’s FDA-Approved Kinase Inhibitor Library contains 280 marketed drugs with proven kinase inhibitory activity. These kinases include Insulin/IGF Receptors、PI 3-Kinase、CaM Kinase II、JAK、PKA、CDK、JNK、PKC、CKI II、MAPK、RAF、EGFR、MEK、SAPK、GSK、MLCK、Src-family、IKK、PDGFR、VEGFR etc. FDA-Approved Kinase Inhibitor Library is a powerful tool for kinase drug development and related research.

Oxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and a biological system's ability to readily detoxify the reactive intermediates or repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. In humans, oxidative stress is thought to be involved in the development of atherosclerosis, heart failure, myocardial infarction, cancer, infection etc. Antioxidants are a class of compounds that counteract oxidative stress and reduce oxidative damage. The TargetMol Antioxidant Compound Library is a unique collection of 1330 small molecules with inhibitory effects on oxidative stress and is a useful tool for high-throughput screening and high-content screening in the study of oxidative stress.

TargetMol created the L4020 NO-PAINS Compound Library that applied the PAINS filter, remaining 9555 small molecules that are suitable for new drug development, signaling pathway research, drug repurposing and other research.

A unique collection of 3720 natural products for high throughput screening (HTS) and high content screening (HCS);