Other Proteins

Human CD276 (Q5ZPR3, 29 a.a. - 466 a.a.) partial recombinant protein with His tag at C-terminus expressed in Sf9 cells.

Mouse Cd276 (Q8VE98, 29 a.a. - 248 a.a.) partial recombinant protein with His tag at C-terminus expressed in Sf9 cells.

Human CD320 (Q9NPF0, 31 a.a. - 229 a.a.) partial recombinant protein with hIgG-His tag at C-terminus expressed in Sf9 cells.

Human TNFRSF8 (P28908, 19 a.a. - 379a.a.) partial recombinant protein with His tag at N-terminus expressed in <i>Escherichia coli</i>.

Human CD33 (P20138, 18 a.a. - 259 a.a.) partial recombinant protein with hIgG-His tag at C-terminus expressed in Sf9 cells.

Human CD34 (P28906, 32 a.a. - 290 a.a.) partial recombinant protein with His tag at C-terminus expressed in Sf9 cells.

GenScript Ni Resin FF is a 6% highly cross-linked agarose medium covalently coupled to a chelating agent that binds Ni2+ by three coordination sites for high-affinity purification of polyhistidine-tagged recombinant proteins.

STING (stimulator of interferon genes), also known as TMEM173 (transmembrane protein 173), is a crucial protein in innate immunity. It is a membrane protein involved in the response to foreign DNA in hematopoietic lineage cells, such as NK and T cells, myeloid cells, and monocytes. It is also found in the retina, heart, and other tissues. STING gets activated by DNA sensors and triggers IFN (type I interferon) production, by stimulating TBK1, which then phosphorylates STAT6 (signal transducer and activator of transcription 6) or IRF3 (interferon regulatory factor 3). These in turn activate the expression of genes linked to immune responses. It can also function as a DNA sensor, by binding directly to the cyclic di-GMP. More recently STING€™s role in controlling ROS (reactive oxygen species) formation and that loss of STING reduces DNA damage have been identified. The development the STING agonist that be beneficial in combinatory cancer therapy.