Results for Other Proteins ( 64688 )
Actins are highly conserved within the eukaryotic kingdom and exist in higher eukaryotes as multigene families. The different actin isoforms can show distinct cellular and sub-cellular expression and localization. It has been demonstrated that different isoforms have subtly different biochemical properties in vitro which supports functional diversity within isotypes in vivo. Monomeric actin (G-actin) can self assemble (polymerize) into microfilaments (F-actin), the fundamental unit of the actin cytoskeleton. It is involved in a large number of cellular processes, including muscle contraction, lamellopodial extrusion, cell locomotion, cytokinesis, intracellular transport and cytoplasmic streaming. AKL95, Actin protein that has been purified from rabbit skeletal muscle by the method of Pardee and Spudich is between 95- 97% pure. Possible contaminants may include α-actinin (100 kDa), actin doublets (86 kDa) or Cap Z (33 kDa). Muscle actin has an approximate molecular weight of 43 kDa.
- Ref: 230-00003-100
Human BCMA, known as TNFRSF17, BCM, BCMA, CD269, and TNFRSF13A, GenBank Accession No. NM_001192, a.a. 1-54, with C-terminal Avi-tag fused to the Fc portion of Human IgG1, and labeled with phycoerythrin (PE), expressed in a HEK293 cell expression system. MW = 34 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.