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    Results for Chemicals ( 1320 )

      • PROTAC FAK degrader 1

        Ref: T13840
        Sizes: 1 mg, 5 mg, 10 mg

        PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) (IC50 of 6.5 nM).

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      • PROTAC K-Ras Degrader-1

        Ref: T13844
        Sizes: 1 mg, 5 mg, 10 mg

        PROTAC K-Ras Degrader-1 is potent degrader of K-Ras based PROTAC.

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      • PROTAC SGK3 degrader-1

        Ref: T13847
        Sizes: 1 mg, 5 mg, 25 mg, 50 mg, 10 mg, 1 mL

        PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a PROTAC coupler that targets SGK3 and binds ligand to VH032 VHL, which induces degradation of endogenous SGK3.PROTAC SGK3 degrader-1 inhibits GDC0941-induced proliferation of cancer cells.CAS 번호5017-88-83-4

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      • PROTAC BET Degrader-1

        Ref: T13849
        Sizes: 5 mg, 25 mg, 10 mg, 1 mL

        PROTAC BET Degrader-1 is a potent degrader of BET based on PROTAC.

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      • PROTAC BET degrader-3

        Ref: T13850
        Sizes: 5 mg, 25 mg, 10 mg

        PROTAC BET Degrader-3 is a potent degrader OF BET based on PROTAC.

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      • SMARCA-BD ligand 1 for Protac dihydrochloride

        Ref: T13890
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg

        SMARCA-BD ligand 1 for Protac dihydrochloride binds to the BAF ATPase subunits SMARCA2, and used for degrading SMARCA2, based on PROTAC.

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      • PROTAC BRD9-binding moiety 1 hydrochloride

        Ref: T13915L
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL

        PROTAC BRD9-binding moiety 1 hydrochloride binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.

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      • PROTAC ERRα ligand 1

        Ref: T15191
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg, 1 mL, 2 mg

        PROTAC ERRα ligand 1 is an α (ERRα) antagonist of estrogen-related receptor (IC50s of 0.04 and 2.8 μM for ERRα and ERRγ, respectively).

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      • Gefitinib-based PROTAC 3

        Ref: T5437
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 2 mg

        Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively[1].

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