Antibiotics & Metabolites

Chlortetracycline Degradation Set

Activity: Purine antimetabolite and immunomodulator . Function/Pharmacology: Purine antimetabolite drug used to treat acute lymphocytic leukemia, Crohn’s disease, ulcerative colitis, and inflammatory bowel disease.1 It inhibits DNA synthesis by inhibiting the production of purine containing nucleotides. The immunomodulatory activity of 6-Mercaptopurine is mainly the result of the 6-MP metabolite 6-thioguanine triphosphate (6-TGTP) binding to small GTPase Rac1.2 Chemical Name: 3,7-Dihydropurine-6-thione monohydrate

Mebeverine acid (Mebeverine metabolite Mebeverine acid) is a secondary metabolite of Mebeverine and can be used as a marker of oral exposure to Mebeverine.

LGE-899 (Sonidegib metabolite M48) is a main metabolite of Sonidegib which is an inhibitor of the hedgehog pathway. The Tmax of LGE-899(60 h) is much longer than Sonidegib.

Antimicrobial spectrum: Gram-positive and Gram-negative bacteria, Pseudomonas

beta-lactam antibiotic

against mycobacteria

ABT-1812 is a bio-active chemical.

AG-2000 Free Base is a bio-active chemical. Detailed information has not been published.