Lab Tools

NisslFluor™ Green Nissl stain will stain the soma and proximal reaches of dendrites, cytoplasm, and nuclei of neurons a fluorescent green color under blue light excitation. Nissl substance is not normally found in the axon hillock or the axon itself. NisslFluor™ Green will be of high contrast, resolution, and brightness and resistant to fading. Visible under blue light (450-495 nm) excitation. This fluorochrome demonstrates little fluorescence under green light excitation (500ﾖ570 nm) or UV excitation (330-380 nm).</div>

LipoFluor-P2™ is a cell-permeant stain for intracellular lipid droplets and the endoplasmic reticulum. This tracing reagent can be used on live and fixed cells and is compatible with other dyes. LipoFluor-P2™ has a large Stokes Shift, shows excellent resistance to photobleaching, and demonstrates low cytotoxicity.

LipoFluor-ER2™ is a cell-permeant stain for the endoplasmic reticulum with unique spectral properties, which makes it particularly useful for antibody double- and triple-labelling experiments. LipoFluor-ER2™ is highly compatible with green, red and far-red fluorophore-labelled antibodies and has been successfully used to image the endoplasmic reticulum in human and other mammalian cell lines. It passively diffuses across the plasma membrane into the cell, stains at low concentrations and has minimal cytotoxic effects. This tracing reagent can be used on live and fixed samples, is compatible with other dyes, shows excellent resistance to photobleaching and demonstrates low cytotoxicity.

HQ-O Ready-To-Dilute (RTD^TM) Stain Reagent is designed to label amyloid plaques in paraffin-embedded or freshly cut frozen tissue sections. As a fluorescent zinc chelator, HQ-O is unique as it takes advantage of the known presence of concentrated zinc in amyloid plaques. Studies with HQ-O revealed that fluorescent plaque-like structures are only seen when synthetic Aβx-42 is aggregated in the presence of zinc. Under blue light excitation, plaque structures appear bright green fluorescent in the brain parenchyma, correlating closely with plaque structures observed following Aβ antibody staining. HQ-O RTD^TM staining reagent is compatible with other fluorophores, such as DAPI, Hoechst and ethidium bromide, as well as fluorescent-labelled antibodies with emission spectra in the blue and/or red emission range of fluorescent microscopes. Due to its zinc-chelating characteristics, HQ-O RTD^TM staining reagent may visualize globular structures within blood vesse