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Chemicals & Small Molecules

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    Results for Chemicals & Small Molecules ( 84949 )

      • (S, R)-LSN 3318839

        Ref: T63166L
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg
        From: €222.00

        (S, R)-LSN 3318839 is an allosteric modulator of the glucagon-like peptide-3318839 receptor (GLP-1R) that has demonstrated powerful hypoglycemic effects in animal models alone or in combination with sitagliptin.

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      • Aβ-IN-1 TFA

        Ref: T63208L
        Sizes: 1 mg
        From: €222.00

        Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.

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      • Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl

        Ref: T63898
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL
        From: €222.00

        Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is a dual PPARα/γ agonist with EC50 of 0.358μM and 1.21μM. Benzo[b]thiophene-7-propanoic acid, α-methoxy-4-[2-(5-methyl-2-phenyl-4-oxazolyl)ethoxy]-, (αR)- is the R-isomer of Aleglitazar.

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      • Triton X-100

        Ref: T64297
        Sizes: 100 g
        From: €48.00

        Triton X-100 is a non-denaturing detergent that solubilizes lipid membranes. Triton X-100 is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Triton X-100 is listed as an excipient in certain vaccines including split virus influenza vaccines. Triton X-100 is a nonionic surfactant [1] [2].

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      • FA16

        Ref: T64357
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €222.00

        FA16 is a selective, metabolically stable ferroptosis inducer with an IC50 value of 1.26 μM.FA16 is a derivative of 2-(trifluoromethyl)benzimidazole.FA16 inhibits the cystine/glutamate inverse transporter protein (system Xc-)-mediated exchange of intracellular glutamate for extracellular cystine.FA16 significantly inhibited tumor growth in a HepG2 xenograft tumor model. HepG2 xenograft tumor model significantly inhibited tumor growth.

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      • ES9-17

        Ref: T64368
        Sizes: 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL, 200 mg
        From: €57.00

        ES9-17, an analog of ES9 (endosidin9), is an inhibitor of clathrin-mediated endocytosis (CME). ES9-17 inhibits the uptake of FM4-64 and transferrin. ES9-17 inhibits root growth of Arabidopsis seedings.

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      • Dynamin IN-2

        Ref: T64369
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 10 mg, 1 mL
        From: €451.00

        Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).

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      • JI6

        Ref: T64370
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €186.00

        JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor. JI6 exhibits IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits c-Kit and JAK3, with IC50s of ∼500 and ∼250 nM, respectively. JI6 has research value in acute myeloid leukemia.

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      • Antiproliferative agent-15

        Ref: T64391
        Sizes: 1 mg, 5 mg, 25 mg, 100 mg, 50 mg, 500 mg, 10 mg
        From: €222.00

        Antiproliferative agent-15 is a reagent with anticancer activity. Antiproliferative agent-15 showed antiproliferative activity against human colon cancer (HCT116 and HCT15) and brain cancer (LN-229 and GBM-10).

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