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Tetramethylrhodamine-5-(and-6) C2 maleimide is a good alternative to tetramethylrhodamine-5-(and-6)-maleimide with excitation/emission wavelength at 544/572 nm. Its spectral characteristics are very close to those of tetramethylrhodamine-5-(and-6)-maleimide (+2 nm). It is 40% less expensive compared to tetramethylrhodamine-5-(and-6)-maleimide, and can be used for thiol modification of proteins, antibodies and peptides.