Galectin-3 (Mac-2) is a β-galactoside-binding lectin expressed in a variety of tissues and cell types (incl. activated macrophages, eosinophils, mast cells, dendritic cells, kidney cells, and sensory neurons).
Galectin-3 is a promiscuous protein modulating a diverse set of cellular functions such as cell adhesion, cell-matrix interactions, cell migration, macrophage activation, and apoptosis.
It has been described to play a role in many pathological states such as fibrosis, cardiovascular diseases and cancer.
Due to the role of galectin-3 in various pathologies, it is increasingly being investigated as a potential diagnostic marker and therapeutic target.
Being able to access well-characterized research tools enabling Galectin-3 expression studies is therefore crucial.
In this context, Cedarlane has recently released a 100% validated monoclonal antibody (clone M3/38) valid for a broad range of applications.
| Format | Reactivity | Applications | Size | Cat nr |
| Purified | Human/Mouse | Cryostat section, ELISA, FCM, IF, WB/IP | 100 µg | 007CL8942AP |
| Biotin | Human/Mouse | Cryostat section, ELISA, FCM, IF, WB/IP | 100 µg | 007CL8942B |
| FITC | Human/Mouse | FCM, IF | 100 µg | 007CL8942F |
| Low endotoxin | Human/Mouse | Cryostat section, ELISA, FCM, IF, WB/IP | 500 µg | 007CL8942LE |
Also of interest
You might also like to take a look at this range of Galectin-3 ELISA kits, available in Europe through tebu-bio.
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