Chemicals & Small Molecules

C8-Alkyne-dCTP is easily incorporated into DNA by PCR instead of dCTP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dCTP.

C8-Alkyne-dCTP is easily incorporated into DNA by PCR instead of dCTP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dCTP.

5-Ethynyl-dUTP (5-EdUTP) is easily incorporated into DNA by PCR instead of dUTP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dUTP.

5-Ethynyl-dUTP (5-EdUTP) is easily incorporated into DNA by PCR instead of dUTP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dUTP.

Alkyne-dATP (7-deaza-7-Ethynyl-dATP) is easily incorporated into DNA by PCR instead of dATP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dATP.

Alkyne-dATP (7-deaza-7-Ethynyl-dATP) is easily incorporated into DNA by PCR instead of dATP using polymerases like Pwo, Deep Vent exo- or KOD XL. The resulting stable and modified PCR fragment is now ready for further functionalization by Click Chemistry. We recommend a substitution of 1 – 10% of dATP.

Pseudo Uridine modified mRNA exhibits longer half-life, a better translation efficiency and its immunological properties are improved.

Pseudo Uridine modified mRNA exhibits longer half-life, a better translation efficiency and its immunological properties are improved.

Anti Reverse Cap Analog (ARCA) modified mRNA exhibits a longer half-life and the translation efficiency is increased by using this cap analog used during in vitro transcription for the generation of capped transcripts.