Nucleic Acids

This C8-Alkyne-dU-phosphoramidite, containing a C8-Spacer, is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency.

This C8-Alkyne-dU-phosphoramidite, containing a C8-Spacer, is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency.

This C8-Alkyne-dC-phosphoramidite, containing a C8-Spacer, is used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with excellent coupling efficiency.

5-Ethynyl-dU-CEP is an universal alkyne modifier that can be used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with high coupling efficiency.

5-Ethynyl-dU-CEP is an universal alkyne modifier that can be used under standard conditions for solid phase synthesis of oligonucleotides. It has shown to be incorporated into DNA oligomers with high coupling efficiency.

This TIPS-EdU phosphoramidite can be used instead of the EdU-CEP under standard conditions for solid phase synthesis. The protecting group reduces the risk of side products. The oligo is deprotected after the synthesis leading to ethynyl modified oligonucleotides.

This TIPS-EdU phosphoramidite can be used instead of the EdU-CEP under standard conditions for solid phase synthesis. The protecting group reduces the risk of side products. The oligo is deprotected after the synthesis leading to ethynyl modified oligonucleotides.

This TIPS-EdU phosphoramidite can be used instead of the EdU-CEP under standard conditions for solid phase synthesis. The protecting group reduces the risk of side products. The oligo is deprotected after the synthesis leading to ethynyl modified oligonucleotides.

With this phosphoramidite it is possible to introduce alkyne modified A in the oligonucleotide. After standard solid phase synthesis, the final oligo is ready for subsequent click reaction.