Nucleic Acids

DNA was prepared from cell line WM3438. WM3438 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line contains wild type BRAF, N-RAS, c-KIT and CDK4 genes. WM3438 cells produce xenograft tumors when injected into immunocompromised mice.

Total RNA was prepared from cell line WM3438. WM3438 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line contains wild type BRAF, N-RAS, c-KIT and CDK4 genes. WM3438 cells produce xenograft tumors when injected into immunocompromised mice.

Total RNA was prepared from cell line WM3438. WM3438 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line contains wild type BRAF, N-RAS, c-KIT and CDK4 genes. WM3438 cells produce xenograft tumors when injected into immunocompromised mice.

Total RNA was prepared from cell line WM3438. WM3438 is a human metastatic melanoma cell line that displays a mesenchymal morphology. This cell line contains wild type BRAF, N-RAS, c-KIT and CDK4 genes. WM3438 cells produce xenograft tumors when injected into immunocompromised mice.

DNA was prepared from cell line WM3456. WM3456 is a human metastatic melanoma cell line that displays a thin elongated, fibroblastic morphology. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation.  WM3456 cells produce xenograft tumors when injected into immunocompromised mice.

DNA was prepared from cell line WM3456. WM3456 is a human metastatic melanoma cell line that displays a thin elongated, fibroblastic morphology. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation.  WM3456 cells produce xenograft tumors when injected into immunocompromised mice.

Total RNA was prepared from cell line WM3456. WM3456 is a human metastatic melanoma cell line that displays a thin elongated, fibroblastic morphology. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation.  WM3456 cells produce xenograft tumors when injected into immunocompromised mice.

Total RNA was prepared from cell line WM3456. WM3456 is a human metastatic melanoma cell line that displays a thin elongated, fibroblastic morphology. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation.  WM3456 cells produce xenograft tumors when injected into immunocompromised mice.