Lipids & Polymers

ATX-001, also know as O-11280, is an ionizable lipid with a sulfur bond near the polar head and a pair of unsaturated tails. It is useful for Development of Lipidoid Nanoparticles for siRNA, mRNA, and vaccine Delivery. Reagent grade, for research use only.

DODAC is a cationic lipid with a pair of unsaturated tails. This complex can serve as a well-defined intermediate in the preparation of DNA-lipid particles (DLPs) with many potential applications for delivery of polynucleotides in vitro and in vivo. Reagent grade, for research use only.

Biotin-Onp is a conjugate of biotin and an oligonucleotide containing a carboxy terminal peptide. Biotin-Onp is a peptide hormone that has been shown to be involved in the regulation of several autoimmune diseases. Reagent grade, for research use only.

N-Biotinyl-NH-(PEG)2-COOH . DIPEA (20 atoms) is a biotin linker containing a carboxylic acid group. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. Reagent grade, for research use only.

Fmoc-Asp(biotinyl-PEG)-OH is a biotinylation reagent with a terminal Fmoc group. The terminal biotinylation can react with amine molecules in the presence of activator EDC or HATU. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research use only.

Fmoc-Glu(biotinyl-PEG)-OH is a biotinylation reagent with a terminal Fmoc group. The terminal biotinylation can react with amine molecules in the presence of activator EDC or HATU. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. Reagent grade, for research use only.

NHS-PEG4-biotinidase resistant biotin is a biotinylation reagent with a terminal NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal biotinylation can react with amine molecules in the presence of activator EDC or HATU. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research use only.

TFP-PEG4-biotinidase resistant biotin is a biotin and TFP ester end group. The biotin group is reactive with primary amino (-NH2) compound to form stable, irreversible amide bonds. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. Reagent grade, for research use only.

TFP-PEG12-biotinidase is a biotin and TFP ester end group. The biotin group is reactive with primary amino (-NH2) compound to form stable, irreversible amide bonds. The hydrophilic PEG spacer arm imparts water solubility that is transferred to the biotinylated molecule. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. Reagent grade, for research use only.