Cell Line

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to academic organisations (not for profit).

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to private organisations.

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to academic organisations (not for profit).

The EGFR L861Q Reference Standard is genomic DNA derived from a highly characterized homozygous diploid HCT116 cell line, genetically modified with advanced genome editing technology to include the mutation L861Q in EGFR on both chromosomes. The variant allele frequency (VAF) is 100%, and can be diluted using the corresponding wild-type standard to reach lower VAF. This reference standard can be used to assess the performance of your NGS, sanger sequencing and qPCR assay, including the limit of detection, accuracy, and precision.

CF-1 Mouse Embryonic Fibroblast (MEF) feeder cells, Mitomycin-C treated. Mitotically inactivated fibroblasts should be used as a support layer for embryonic stem (ES) cells and induced pluripotent stem (iPS) cells.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant HEK293 cell expressing firefly luciferase gene under the control of NF-κB response elements with constitutive expression of human OX40 (Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, and CD134, GenBank Accession No. NM_003327)

Please note this product may be subject to fees, we invite you to contact your local office. The Myc Reporter - HCT116 cell line contains the firefly luciferase gene under the control of Myc responsive elements stably integrated into HCT116 cells, a human colon cancer cell line. HCT116 contains a mutated ?beta-catenin which leads to the accumulation of β?-catenin and constitutive activation of downstream Myc that induces the expression of Myc luciferase reporter. The cell line is validated for the inhibition of the expression of Myc luciferase reporter.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cell constitutively expressing full-length human CD137L (NP_003802.1). Surface expression is confirmed by flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018).