Cell Culture Products

ThawSTAR Power Supply and Adaptors

BioT LN2 Transporter

BioT Transporter Dry Ice Retainer (DIR)

PIM (ABS) – Human AB Serum is a required additive for PIM(R), PIM(S), and PIM(T) islet specific tissue culture media. It is shipped separately as a frozen component to permit the extended shelf life of this media without the AB Serum. Once it is thawed and added to the media, it is recommended that the expiration date be considered to be 60 days from the date of the PIM(ABS) addition. It is collected, screened, and frozen until ready for cGMP manufacturing which includes heat inactivation followed by sterile filtration and bottle filling. All lots of PIM(ABS) are screened for compatibility with human islets prior to release in addition to the standard QC/QA testing and analysis.

PIM(S)® is a new Prodo Labs islet specific media that is manufactured under cGMP conditions for use in human islet culture for clinical transplantation and for research. It is designed for long term tissue culture of islets from 2 to 21 days at 37oC. It is enhanced with specific components that permit long term culture of healthy islets that maintain their glucose responsiveness, insulin content, and suitability for implantation. It currently is designed to be used with 5% Human AB Serum that is pretested for islet suitability. It does not contain any animal proteins or growth factors and has a glucose concentration of 5.8 mM.

StemBeads® FGF2 is a patented growth factor supplement that offers a novel way to culture cells with native Fibroblast Growth Factor 2 more efficiently. FGF2 is key for growth of human induced pluripotent stem cells (iPSCs), fibroblast cells, wound healing cells such as macrophages, cancer cells, and neural progenitor cells (NPCs). StemBeads® FGF2 are microbeads composed of an FDA approved, biodegradable PLGA polymer that is loaded with native recombinant human FGF2. Controlled delivery and stable levels overcome the 4.5 hour half-life (Figure below) of FGF2 and improve cell cultures while saving researchers valuable time and resources.