Cell Line

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to academic organisations (not for profit).

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to private organisations.

Please note that an MTA needs to be signed prior to purchase of this product, we kindly request that you contact your local office. This product is provided at this price to academic organisations (not for profit).

CF-1 Mouse Embryonic Fibroblast (MEF) feeder cells, Mitomycin-C treated. Mitotically inactivated fibroblasts should be used as a support layer for embryonic stem (ES) cells and induced pluripotent stem (iPS) cells.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant HEK293 cell expressing firefly luciferase gene under the control of NF-κB response elements with constitutive expression of human OX40 (Tumor Necrosis Factor Receptor Superfamily Member 4, TNFRSF4, and CD134, GenBank Accession No. NM_003327)

Please note this product may be subject to fees, we invite you to contact your local office. The Myc Reporter - HCT116 cell line contains the firefly luciferase gene under the control of Myc responsive elements stably integrated into HCT116 cells, a human colon cancer cell line. HCT116 contains a mutated ?beta-catenin which leads to the accumulation of β?-catenin and constitutive activation of downstream Myc that induces the expression of Myc luciferase reporter. The cell line is validated for the inhibition of the expression of Myc luciferase reporter.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cell constitutively expressing full-length human CD137L (NP_003802.1). Surface expression is confirmed by flow cytometry.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018).

Please note this product may be subject to fees, we invite you to contact your local office. This cell line expresses a surface human GITR (glucocorticoid-induced TNFR family related gene; TNFRSF18; CD357) and an NF-κB luciferase reporter construct that are stably integrated into the genome of Jurkat T-cells. The firefly luciferase gene is controlled by 4 copies of NF-κB response element located upstream of the TATA promoter. Following activation by stimulants, endogenous NF-κB transcription factors bind to the DNA response elements to induce transcription of the luciferase gene. The cells have been validated using purified human GITRL and anti-GITR neutralizing antibody.