Hyaluronan Enzyme-Linked Immunosorbent Assay (HA ELISA) - EA KIT

The Hyaluronan Enzyme-Linked Immunosorbent Assay (HA ELISA) a competitive 96-well assay offers a simple effective method for determining Hyaluronic Acid (HA) levels in human and animal biological fluids or cell supernatants.Assay Range: 50-1600 ng/mlSensitivity: 25 ng/mLSample considerations: The HA ELISA detects HA molecules that are as small as 6.4 kDA.4Hyaluronic acid (HA) is a high molecular weight anionic polysaccharide (1 000-10 000 kD) composed of repeating disaccharides. It is one of several glycosaminoglycan components of the extracellular matrix of connective tissue.Free HA is taken up by the liver where it is degraded and recycled. Many chronic liver diseases including infection (hepatitis B or C) toxicity (alcohol and drugs) genetic (hemochromatosis) autoimmunity and malignancy result in liver inflammation which can progress to liver fibrosis and cirrhosis; causing impairment of liver function and resulting in a rapid increase in circulating HA levels.Data indicate