Cell Line

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Jurkat cell line constitutively expressing a full length human TIGIT (T cell Immunoreceptor with Immunoglobulin and ITIM domain; VSTM3), and a firefly luciferase gene under the control of nuclear factor of activator T cells (NFAT) response element. Both TIGIT and NFAT constructs have been stably integrated into Jurkat cells. TIGIT expression has been confirmed by Western Blot, and TIGIT-specific NFAT response has been validated using a TIGIT ligand, CD155 (PVR).

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cell constitutively expressing a membrane bound, engineered T cell receptor (TCR) activator.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, low affinity (F158) variant and Fcγ chain.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human FcγRIIIa, high affinity (V158) variant and Fcγ chain.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cells constitutively expressing human PD-L1 (Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7- H1), GenBank accession #NM_014143).

Please note this product may be subject to fees, we invite you to contact your local office. PAI-1 Reporter (Luc)-Mv1 Lu cell line is designed for monitoring transforming growth factor β (TGF-β)-induced plasminogen activator inhibitor-1 (PAI-1) expression. Transforming growth factor-β (TGF-β) is a potent regulator of cellular differentiation, proliferation, migration, and protein expression. PAI-1 Reporter (Luc) -Mv1 Lu cell line contains a firefly luciferase gene under the control of PAI-1 responsive elements stably integrated into Mv1 Lu (NBL-7) cells, showing TGF-β pathway response. This cell line is validated for the TGF-β response to the induction of PAI-1 gene expression through luciferase activity.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cell transfected with empty expression vector containing the hygromycin resistance gene. This cell line serves as a negative control for: TCR Activator - CHO Recombinant Cell line, #60539; DAT CHOK1 Recombinant Cell Line, #60558; and NET - CHOK1 Recombinant Cell , #60557  

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant CHO-K1 cells constitutively expressing human CD155 (Poliovirus receptor, Nectin-like protein 5, GenBank accession #NM_006505) and an engineered T cell receptor (TCR) activator.

Please note this product may be subject to fees, we invite you to contact your local office. Recombinant Raji cell expressing an engineered T cell receptor (TCR) activator.