Antibiotics & Metabolites

Solution in 0.9% NaCl

Activity: Bioactive gut microbial metabolite . Function/Pharmacology: A microbial-mammalian host co-metabolite which increases with age1 and especially in extreme longevity2. Gut-microbiota-dependent PAG is associated with cardiovascular disease pathogenesis3 via action at adrenergic receptors4. Plasma PAG levels may be a valuable indicator for predicting coronary in-stent restenosis.5 Chemical Name: (S)-5-Amino-5-oxo-2-(2-phenylacetamido)pentanoic acid

tetranor-PGEM is the major urinary metabolite of PGE1 and PGE2, and is used as a marker of PGE2 biosynthesis.[1],[2] About 15% of an infused dose of PGE2 appears as this metabolite in the urine of humans. Normal healthy males excrete 7-40 μg of tetranor-PGEM over a 24-hour period.[1]

N-Demethyl Ivabradine Hcl is a specific inhibitor of the funny channel.N-Demethyl Ivabradine Hcl is a metabolite of Ivabradine.