Scientific Library
3D monitoring of cell movement through Collagen I
The transition from non-invasive phenotype to invasive phenotype of tumor cells marks the switch from a benign tumor to a more malignant form of cancer. Understanding the mechanisms underlying this hallmark
Genetically encoded fluorescent biosensors for live cell discovery
In drug discovery screening campaigns as well as in fundamental research activities, cellular parameters have to be measured and monitored in living cells regularly. Often fluorescent dyes are used to
Cancer Immunotherapy: Generate your PD-L1 target cell line
In a recent post, I invited you to discover a cell
Screen for inhibitors of PD-1 signalling with a complete cellular assay system
Immunotherapy represents a field in Drug Discovery which is quickly developing and leading to significant progress in treatments of a number of diseases, especially cancer. The approach is based on inducing,
New cancer treatment may reawaken the immune system
Cancer is a disease caused by abnormal cell growth. The cells’ genetic material is corrupted and the metabolic processes do not interact well with them anymore. They grow unchecked, mostly in the form