Page 6 - Scientific Library
Article
Return of SIRT1 deacetylase - Why is SIRT1 so attractive in Drug discovery and Stem cell research?
May 06, 2014
SIRT1 is a NAD dependent class III Histone Deacetylase (HDAC). The tumor suppressor p53 is not the unique SIRT1 substrate. SIRT1 also deacetylates various key protein targets (PTEN, FOX, HIF-1