Azide-PEG8-Val-Cit-PAB-MMAE - 5 MG

Azide-PEG8-Val-Cit-PAB-MMAE is a cleavable ADC linker which contains an azide, a PEG spacer, a Val-Cit dipeptide, a PAB group, and an MMAE warhead. The azide is free to participate in click chemistry with terminal alkynes or strained cyclooctynes such as DBCO or BCN. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient MMAE payload delivery via an elimination mechanism within the PAB structure.

Supplier Catalog Number

BP-40188

Shipping conditions

Room temperature

Storage Temperature

-20°C

Supplier name

BroadPharm

CAS Number

0
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Additional information

Formula: C77H129N13O21
Molecular Weight: 1572.96118 Da