Scientific Library
Human Primary Sebocyte assay for compound testing on lipid metabolism
Sebocytes belong to the epidermal ecosystem together with hair follicules or in sebaceous glands. Sebocytes play a key role in skin health by producing sebum. These cells are now at the center of researchers'
Measure antioxidative capacities of your samples
Free radicals and Reactive Oxygen Species (ROS) are highly reactive molecules generated by normal cellular processes, environmental stress, and UV irradiation. ROS react with numerous cellular components
AAV - advantages for Gene delivery in vivo
Adenoassociated viruses (AAV) are small (20-30 nm), ssDNA, non-enveloped and replication-defective viruses that infect human and other primate species, but which, up to now, have not been reported as being
Easy and sensitive methods to measure antioxidative potential
Free radicals and reactive oxygen species (ROS) are highly reactive molecules that are generated by normal cellular processes, environmental stress, and UV irradiation. ROS react with cellular components,
Adenovirus: weapons of mass transduction for gene delivery
Adenovirus (AV) are non-enveloped and non-integrative icosaedral viruses. Recombinant AV (genetically modified with respect to the wild-type in order to lose their capacity of replication) are widely used
PBMCs & drug development
Use of human samples including peripheral blood mononuclear cells (PBMCs)Â in drug discovery is critical for increasing the chances of success for a small molecule screen hit. A review based on recent
HD-LCI video of HUVEC Transfection with Cytofect Kit
See human cells glow with green fluorescent protein in this time-lapse video. These images were captured over 20 hours via Lumascope 620.
[youtube https://www.youtube.com/watch?v=k5esUe_rrr4]
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High Definition
New in vitro cellular model for human Lipodystrophy
Lipodystrophies are disorders characterized by complete or selective loss of adipose tissue from various regions of the body. They might lead to severe metabolic disorders. The development of reliable
Anti cellulite compound evaluation with in vitro adipocyte-assays
Mechanisms leading to cellulite formation is complex. It involves lipid regulatory pathways and proinflammatory cross-talk that represent promising molecular targets in cosmetology. This post introduces
Cost-efficient pre-optimized transfection reagents
The main challenge when choosing a transfection reagent is that we don't know how it will work with our own cell type of interest. It is also time consuming to find the optimal conditions. Well, here's
Cell-based assays with hPBMCs for cell therapy and drug discovery
Human Peripheral Blood Mononuclear Cells (hPBMCs) are essential for designing cellular models to be used in cell therapy and drug discovery research programs [1-7, 12]. Being able to access reliable and