Scientific Library

In my previous post Small GTPases: Measuring small G protein activation I looked at state-of the-art methods for measuring the activation of small G proteins,

You suspect your protein binds to microtubules? That it might stabilize or destabilize these filamentous structures? Then this post is here to help you to find a meaningful assay to validate your assumption.

Recently, I issued a post about a method which allows measuring microtuble binding capabilities of proteins of interest

Trpytophan (trp) is an important and essential amino acid that has a variety of functions within the cell. In addition to being incorporated

Interleukin-17 (IL-17) is a family of 6 closely related cytokines, designated IL-17A-F, that play a central role in mediating inflammation, autoimmunity,

Over the past months, we have released a number of posts introducing inhibitor screening assays intended to investigate immuno checkpoint

There is an increasing demand for new cholesterol-lowering therapies in addition to existing treatments (e.g. targeting statins). The pharmacological inhibition of PCSK9-mediated LDLR degradation

Extracellular adenosine 5'-triphosphate (ATP) is released by dying and damaged cells, and it acts on many immune

Today, I'd like to give you an overview about methods in actin research with validated R&D products and kits which will allow you to measure binding to actin and effects on the polymerisation dynamics

Over the last several years, the Immune System has appeared as a central, priority target to fight cancer and various other diseases. Currently,

For many pathologies such as cancer or neurological disorders, it has been found that Histone Deacetylase (HDAC) activity is disrupted, making them promising targets for drug development.