AG-14361 - 10 mg

AG14361 is a potent inhibitor of PARP1 with Ki of <5 nM. It is at least 1000-fold more potent than the benzamides. AG14361 treatment before irradiation statistically significantly increases the sensitivity to radiation therapy. AG14361 enhances the growth-inhibitory and cytotoxic effects of topoisomerase I poisons and increases the persistence of camptothecin-induced DNA single-strand breaks.

Supplier Catalog Number

 27602-2

Shipping conditions

 Cool pack

Storage Temperature

 -20°C

Supplier name

 BPS Bioscience

CAS Number

 328543-09-5
From
€702.00
Total €702.00

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Additional information

CAS Number: 328543-09-5