Page 10 - Scientific Library
Focus on the AKT cell signaling pathway...
AKT (Protein Kinase B or PKB), is a serine/threonine-specific protein kinase with known key involvement in glucose metabolism, apoptosis, cell proliferation, transcription and cell migration.
Enhance phospho-protein identification and recovery for Western blot
Protein phosphorylation analysis is more and more used for cell signaling studies. This post-translational modification regulates the function of numerous proteins in both physiological and disease-related
Focus on 6 cytokine growth factors for cell culture!
Cytokines and growth factors are signaling molecules that control the activities of cells through intercellular communication. Numerous families of diverse molecules are categorized as cytokines and/or
Main factors for different cell types...
In my previous post, we focused on 6 cytokine growth factors for cell culture. This time, we will try to find the best factor for each main cell type.
Proteome, secretome, kinome… What’s it all about?
Proteome is referenced as the result of expression of the whole genome. With the recent developments of genomics, one could consider that this analysis is enough to decipher any biological mechanism...
Specific cytokines & growth factors in... angiogenesis, endothelial cells
Angiogenesis is the growth process of new blood vessels from pre-existing one's. It's a normal physiological process, observed during embryonic development. But it's also a pathological process, essentially
Secretome biomarker identification: tech tips for selecting the most suitable tools
In a previous post, I mentioned that the secretome is becoming a very hot topic in the world of
Specific cytokines & growth factors in... inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Numerous cytokines are present within inflammatory
Specific cytokines & growth factors in... hematology!
Hematology is the study of blood, blood-forming organs and blood diseases. The formation of blood cells is referred to as hematopoiesis. All cellular components of the blood are derived from hematopoietic
Immunotherapy Screening - B7-1 / CD28 and B7-1 / CTLA4 Pathways in Drug Discovery
The treatment of diseases by inducing, enhancing, or surpressing an immune response is referred to as Immunotherapy. T-cell activation and inactivation requires the coordination of various co-inhibitory
Immunotherapy Screening - A focus on PD-1/PD-L1/PD-L2 Pathway in drug discovery
The treatment of diseases by inducing, enhancing, or surpressing an immune response is referred to as Immunotherapy. T-cell activation and inactivation requires the coordination of various co-inhibitory
Immunotherapy - BLTA:HVEM, CD47:SIRPα in drug discovery
The treatment of diseases by inducing, enhancing, or surpressing an immune response is referred to as Immunotherapy. T-cell activation and inactivation requires the coordination of various co-inhibitory