Page 4 - Scientific Library

In my previous post Small GTPases: Measuring small G protein activation I looked at state-of the-art methods for measuring the activation of small G proteins,

You suspect your protein binds to microtubules? That it might stabilize or destabilize these filamentous structures? Then this post is here to help you to find a meaningful assay to validate your assumption.

Recently, I issued a post about a method which allows measuring microtuble binding capabilities of proteins of interest

Trpytophan (trp) is an important and essential amino acid that has a variety of functions within the cell. In addition to being incorporated

Hyaluronic acid (Hyaluronan) belongs to the group of glycosaminoglycans (GAGs), but unlike other GAGs like Heparan sulfate

For humans, IFN-α consists of a group of proteins that are greater than 85% homologous by amino acid sequence.  A lot of individual human IFN-α subtypes have been identified and many have

Interleukin-17 (IL-17) is a family of 6 closely related cytokines, designated IL-17A-F, that play a central role in mediating inflammation, autoimmunity,

The monitoring of ECM components during experimental approaches requires robust and user-friendly in vitro assays. In the past experimental methods (e.g. soluble collagen measurement) were laborious

Over the past months, we have released a number of posts introducing inhibitor screening assays intended to investigate immuno checkpoint

Multicolour fluorochrome reagents have spurred researchers' capacity to analyze cell populations and to isolate cell subsets by flow cytometry. In this post, let's take at look at the advantages of 5 optimized

There is an increasing demand for new cholesterol-lowering therapies in addition to existing treatments (e.g. targeting statins). The pharmacological inhibition of PCSK9-mediated LDLR degradation