As you may already know, Spirochrome have developed a broad range of Live Cell Imaging probes for the staining of DNA, Lysosome, F-Actin and Microtubules.

Based on the use of the Silicon rhodamine-like

For many pathologies such as cancer or neurological disorders, it has been found that Histone Deacetylase (HDAC) activity is disrupted, making them promising targets for drug development. Scientists

In the field of neurosciences, increasing research is being undertaken on neurodegenerative disorders like Parkinson’s and Alzheimer’s diseases, as well as on nerve injury and regeneration. One of the

Plasmid preps are to science what salt is to cooking. They're so common that nobody notices, but nothing can be done without them. There is no mention of this step in any published paper, nobody mentions

Chromatin profiling assays enable the mapping of protein-DNA interactions that influence chromatin modeling and gene expression.
Over the years, Chromatin ImmunoPrecipitation (ChIP) assays became the gold-standard

As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™¹ (optimized inducible overexpression), that can generate functional cells with high consistency

Developed by Epicypher and available in Europe through tebu-bio, CUTANA CUT&RUN and its sister technology CUT&TAG are quickly becoming the preferred approaches for Chromatin Mapping experiments over the

Tips and tricks to design and test qPCR primers - advanced procedure

Design and test your own qPCR primers

1. Find the NCBI Gene page for the gene you would like to study. For example, for Human GAPDH.
2. Scroll

Each of our cells contains our entire genetic heritage: 46 chromosomes inherited from our parents on which there are approximately 25,000 genes.
But if all our cells contain the same information, they

More than two years ago, the whole planet got impacted by COVID-19. Over time, and with the help of our dedicated worldwide scientific research community, we have learnt how to prevent its spread and to

mRNA is a ribonucleic acid used by cells as an intermediate carrier of the genetic information contained in the DNA to synthesize proteins, and corresponds to the copy of one of the two strands of DNA.

Mitochondrial Dynamics and Mitochondria-Lysosome Contacts in Neurogenetic Diseases

In an article published in frontiers in Neuroscience, with the aim to study cellular phenotypes in fibroblasts from