Page 12 - Scientific Library
Using PBMCs in immune cell studies
The availability of human peripheral blood mononuclear cells (PBMC) from healthy individuals and from patients with various diseases allows for many studies on normal and abnormal functions of human immune
Activation & de-activation pathways of hepatic fibrosis
3 fluorogenic substrates for iPS and Stem cells analysis
Methods commonly used for the characterization of iPS or ES cells are based on specific antibody staining
What's Trending in the Molecular Biology World? CRISPR !!!
It's official, CRISPR has officially reached "Breakout" status as a Google search term (see image from Google Trends). The Clustered,
5 reliable research tools to study ERG, USP9X and DUB inhibitor in prostate cancer
In a recent paper published in PNAS, Wang et al. show that the inhibition of the deubiquitinase USP9x by the small molecule WP-1130 is able to induce degradation of the transcription factor E-twenty-six
6 tips for thawing hepatocytes
Cryopreserved hepatocytes contain the major hepatic drug-metabolizing enzymes required to study the four categories of xenobiotic biotransformation: hydrolysis, reduction, oxidation and conjugation. Cryopreserved
Distinctions between homogeneous bulk cancer cell tumors vs. Cancer Stem cell driven tumors by Pr. Clarke
Professor Alan Clarke, (Director of the European Cancer Stem Cell Research Institute) has recently given an overview of how Cancer Stem cell tumors differ from the conventional "homogenous bulk cancer
ChAT+ neurons and neurogenesis by Paez-Gonzalez et al. (Duke University)
Paez-Gonzalez et al. (Duke University) have discovered a new population of choline acetyltransferase (ChAT)+ neurons present in the rodent subventricular zone (SVZ). (1) This niche is known
Actin-Binding Proteins (ABPs) review
Actin filaments are essential for cytoskeleton functions (cell morphology, endocytosis and trafficking, contractility, motility...). In eukaryotic cells, polymerization and depolymerization of actin filaments
Focus on the Hypoxia Pathway...
Hypoxia in tumors is closely associated with tumor aggressiveness and resistance to radio- and chemotherapeutic treatment. Therefore, reliable markers for hypoxia represent both valuable diagnostic markers
Tumour microenvironment - glycosylation
Cancer research is increasingly focusing on the tumour microenvironment (TME). Several studies have shown that tumours depend on external signals for maintenance and expansion. It is therefore needed to
2 means to boost RNA-sequencing
RNA-sequencing (RNA-Seq) bottlenecks start with library preparation! Is it possible to prepare a RNA-Seq library in a simple and fast way? And how to avoid the bottlenecks of current RNA-sequencing library