Page 7 - Scientific Library
Cancer stem cells - friend or foe in the fight against cancer?
Today, following our series on Tumour Microenvironment (TME), and leading on from three recent publications, let's discuss Cancer Stem Cells (CSCs).
CSCs are part of the TME, as they reside in
Basics about insulin and dedicated research tools
Diabetes is a major health concern. And its research can be a nightmare sometimes. tebu-bio strive to offer a comprehensive range of research tools and services to study Obesity, Diabetes, and Metabolic
Efficient screening of PPAR active compounds
Peroxisome Proliferator-Activated Receptors (PPARs) are ligand-activated transcription factors of the Nuclear Receptor superfamily. PPAR active compounds are of significant interest in multiple pharmaceutical
How to easily obtain a highly purified untagged recombinant protein
Isolation of highly purified untagged proteins is crucial in today's R&D programs. Up to now, recombinant protein production approaches were often based on the use of "tags" to make protein purification
Secretome profiling - now quantitative!
For secretome biomarker profiling, several solutions, including arrays allowing to screen up to 1,000 factors, have been available for some time now. These profiling solutions, however, were semi-quantitative
Which endotoxin testing assay in bioproduction?
Pharmaceutical, biotech and medical device industries apply restrictive quality systems in their bio-production processes. Among the numerous parameters controlled daily by scientists, I have selected
Biomarkers associated to poor prognosis in pancreatic cancer
A recent publication by Torres et al. has found that B7-1/CD80, EG-VEGF/PK1, IL-29, NRG1-beta1/HRG1-beta1, and PD-ECGF expressions portend a poor prognosis for patients with pancreatic cancer, and these
SUMO-tag: boost your recombinant protein expression
SUMO-tag gene fusion acts as both a chaperonin and as an initiator of protein folding in both prokaryotic and eukaryotic systems. Addition of this tag enables protein experts to increase the expression
Get your ELISA results before mid-morning coffee!
Believe it or not, some 20 years ago, performing an ELISA would take around 3 days. Now we are used to ELISAs that can be performed in one day, or even before lunch! (OK, sometimes before Spanish lunch
Proteomic profiling tools for your neurobiology studies!
First at all, a quick reminder... Cytokines play important roles in inflammation, innate immunity, angiogenesis and cell growth. They are involved in a lot of disease processes like cancer, obesity and
Which are the best CRISPR-CAS9 strategies?
The CRISPR-CAS9 system may well have opened Pandora's box, but it is also definitely the cornucopia of genome editing.
We can do what we want in the genome: settle a mutation, correct a mutation, insert