Page 2 - Scientific Library
New - you know CRISPR, now it's Prime Editing
This month, a new leap forward in gene editing has been published in Nature under the title 'Search-and-replace genome editing without double-strand breaks or donor DNA'. DOI: 10.1038/s41586-019-1711-4.
3 colour Live Cell Imaging - Actin, Tubulin and DNA
Following on from the popular SiR-Probes, earlier this year Spirochrome introduced new SPY probes, as presented in this post.
Take a few minues to watch this video of the SPYâ„¢ Actin, Tubulin and DNA
New Flipper-TR probes - easily measure membrane tension in cells
Despite its importance in the regulation of many cellular processes, membrane tension is still complicated to measure. And despite valuable insights, the techniques currently available remain complex and
New cutting-edge SPY labelling probes
With the great success of the SIR-probes for efficient labeling of the cell Cytoskeleton, DNA and Lysosome, Spirochrome have just launched a series of 10 new live cell fluorescent tools : The SPYTM probes
What mitochondria related diseases?
All human and living beings have mitochondria. These are tiny cellular organisms present in nearly every cell of an individual. They are located more precisely inside the cells, in their nucleus. The main
How can CRISPR/Cas9 be used to edit genomes?
Genes are key components of our lives. With many other factors, they contribute to shaping us, making people and any other living organism what they are. Genomes, whether human or not, are able to evolve
Why replace fluorescent markers with lanthanide nanoparticles to improve detection?
According to the WHO (World Health Organization), early diagnosis of diseases is one of the key factors in the world to save lives and reduce the cost of treatment. Faced with these recommendations, in
Understanding cellular senescence and oxygen consumption rate
Understanding cellular senescence and oxygen consumption rate
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A recent paper published in Science reported a 50% reduction in mortality and improved immune response in old mice infected with SARS-CoV-2
Relationship between antitumor effects and active oxygen
Relationship between antitumor effects and active oxygen
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ROS (Reactive oxygen species) are highly reactive oxygen species mainly generated during the ATP synthesis process in mitochondria. While it is
Revolutionising Live Cell Imaging: Leveraging Novel Targeting Tools to Unlock New Frontiers in Cellular Research
The development of new probes marks significant progress in live-cell imaging. Peroxi_SPY555 and Peroxi_SPY650 are the first small-molecule probes designed specifically for peroxisome labelling, avoiding
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