Luciferase is the general term given to a class of oxidative enzymes that catalyze reactions that give off light, a process known as bio-luminescence (Fig. 1). In biology,
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Article
How to activate or inhibit autophagy?
November 10, 2016
The term Autophagy was introduced by Christian de Duve during the Ciba Foundation Symposium on Lysosomes – which was held in London in February 1963. In 1974 he was honoured with the Nobel price in
Article
New effective anti-Human IFN neutralizing antibody
January 13, 2017
Neutralizing MAb Anti-Human Interferon Lambda Receptor 1, Clone MMHLR-1 - PBL Assay Sciences at tebu-bio
PBL Assay Sciences offer a new monoclonal antibody to neutralize Human Interferon (IFN) activity,
Article
Fluorescence microscopy: how to improve your Live Cell Imaging
March 09, 2017
For more than 2 years now, the Silicon Rhodamine-like (SiR) technology has allowed the live cell imaging field with fluorescence microscopy to evolve significantly.
Fluorescent SiR-probes have appeared
Article
Stauprimide inhibits c-myc transcription in cancer cells
April 04, 2017
Stauprimide is known to prime Embryonic Stem Cells (ESC) by targeting the c-Myc-activating transcription factor NME2. Its mechanism of action is linked to the inhibition of the nuclear localization of
Article
Obtain clear Western Blot and Immunoprecipitation results
October 03, 2017
Generating high-quality Immunoprecipitation & Western Blot (IP & WB) data has never been easier. See how you can easily achieve this in our Tips & Tricks section to get clean WB-IP.
The TrueBlot® reagents
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Breast Cancer - Popular validated primary antibodies for research and biomarker discovery
October 09, 2017
Use of validated antibodies is primordial for Breast Cancer research and related biomarker discovery. Here, we'll review the main biomarkers involved in this disease and introduce the most popular validated
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Biomolecule conjugation - how to biotinylate with reproducible results?
October 13, 2017
Biomolecule conjugation is critical to many applications such as bead-based assays, ELISA and chromatography by affinity. Unfortunately the classical methods are known to be tedious and with low efficiency.
Article
Bioactive neuronal lipid mediators: a focus on Synaptamide
November 27, 2017
Focus Biomolecules produces a broad range of bioactive lipid mediators as well as many small molecule inhibitors of numerous lipid metabolic pathways for use as cellular probes. These can be supplied
Article
GPR17 and Remyelination: activators and antagonists
November 29, 2017
The absence of mature oligodendrocytes for the repair of demyelination lesions is a critical factor in the pathology of Multiple Sclerosis (MS), and other debilitating CNS disorders of myelination. As
Article
New - 4 Unique IFN Neutralizing reagents
February 19, 2018
PBL Assay Science, the specialists of Interferon related quality reagents, have just released 4 new unique products to be used in neutralization assays. I am pleased to introduce them in this post, in