Page 4 - Scientific Library
3 monoclonals to discriminate free Ubiquitin from linear and polyubiquitin chains
Ubiquitin (Ub) is an 8 kDa highly conserved polypeptide, commonly expressed in eukaryotic cells. Ub is added to lysine residues of the target proteins. This post-translational modification (known as ubiquitination)
How to measure Calcium in cell based assays?
In Pharma screening departments there is a strong need for Ca2+ measurement methods.
Why is this?
2 new Actin and Tubulin live cell imaging stains - without transfection!
Cytoskeletal live cell imaging is extremely powerful when investigating cellular processes such as cytokinesis, motility and organelle transport and organization. The current experimental
Actin staining techniques in fixed and living cells
Actin can be stained in living and fixed cells to determine and follow the structure and function of the cytoskeleton. The actin cytoskeleton is a very dynamic and labile structure in the living cell,
New Fluorescent Labeling and Detection Products
For decades researchers have been using the famous Alexa Fluor® dyes developed by Molecular Probes for everything from flow cytometry to oligonucleotide labeling. These sulfonated forms of common fluorophores
Click Chemistry: What it means for biologists
A few months ago I read a very nice blog post from our friends at TriLink Biotechnologies giving the chemist's perspective on the excitement surrounding "Click
Intracellular Calcium measurement with Fluo-8
G Protein Coupled Receptors (GPCR) and ion channels are important targets in drug development. Both target classes represent membrane proteins which require convenient and robust cell-based assays for
Live Cell Imaging: User results with SiR-Actin & SiR-Tubulin
For one year now, SiR-Actin and SiR-Tubulin, the second generation of tools to stain actin and tubulin in