Page 10 - Scientific Library
A focus on the Wnt Pathway
The Wnt cell signalling pathway is a high-potential therapeutical target in cancer research. It's deeply linked to cellular fate through modulating cell proliferation, mobility, interaction, and polarity.
Find metastatic biomarkers in osteosarcoma!
Early in 2015, researchers of The University of Queensland Diamantina Institute (Australia) have shown a very sensible approach to the discovery of new biomarkers associated to transition from non-metastatic
Genetically encoded fluorescent biosensors for live cell discovery
In drug discovery screening campaigns as well as in fundamental research activities, cellular parameters have to be measured and monitored in living cells regularly. Often fluorescent dyes are used to
Biomarkers of stemness
Stem Cells: a great tool for biomedical research! From the embryo at a very early stage of development, stem cells have two important capabilities: to multiply to infinity by simple division and to give
Cancer Immunotherapy: Generate your PD-L1 target cell line
In a recent post,  I invited you to discover a cell line provided by BPS Bioscience over-expressing the checkpoint
Make sure you detect all your Human IFN-alpha
For humans, IFN-α consists of a group of proteins that are greater than 85% homologous by amino acid sequence.  A lot of individual human IFN-α subtypes have been identified and many have different
How to choose the best 3D technology for your assay?
Cell culture models using 2D substrates have provided important conceptual advances in understanding the biology of cells. However, cells grown on flat 2D surfaces can differ substantially from physiological
Still using MTT or WST-1 for cell counting?
If the answer is yes, I am sure you'll be interested to learn more about WST-8 and our Cell Counting Kit-8 (CCK-8). If the answer is no, and you've already switched to WST-8, just have a look at our
Screen for inhibitors of PD-1 signalling with a complete cellular assay system
Immunotherapy represents a field in Drug Discovery which is quickly developing and leading to significant progress in treatments of a number of diseases, especially cancer. The approach is based on inducing,