Page 5 - Scientific Library
Cancer Immunotherapy: Generate your PD-L1 target cell line
In a recent post, I invited you to discover a cell
CBR-5884 - a Serine biosynthesis inhibitor for cancer research
Metabolic pathways are upregulated in cancer cells to promote their growth and proliferation. The evidence pointing to the requirement of the amino acid serine in tumorigenesis is overwhelming. Serine
30 cancer proteins in one array!
Breaking news for cancer researchers! We are pleased to have recently added innovative cancer Arrays to our product offer. You might tell me that there are a lot of new cancer arrays every year and it's
New Lung Cancer Autoantibody Protein Arrays
Once again, a new product is launched this week for cancer researchers: RayBio® Cancer Autoantibody Protein Arrays. These arrays are semi-quantitative multiplex protein immunoassays developed
Live cell imaging of Actin, Tubulin & DNA - SLAS conference
In the autumn of 2014, we presented new stains to conduct live cell imaging of Actin and Tubulin, which I covered in my post 2 new Actin and Tubulin live-cell imaging stains – without transfection!
How to easily purify your protein with adapted magnetic beads…
…or how to make your protein attractive
Biomagnetic separation is a powerful lab tool in protein biochemistry which can be used in a wide range of applications including analysis tools
New Human Immune Checkpoint Antibody Array
Immune checkpoint molecules play an important role in T cell functionality after TCR/MHC signaling. In fact, blockade of two B7/CD28 family checkpoint molecules, namely CTLA-4 and PD-1, have already demonstrated
New Polyethylene Glycols (PEG) as versatile biochemical linkers
Polyethylene Glycols (aka. PEGs) are biologically inert, non-immunogenic, and hydrophilic molecules. These properties make them very attractive for research and drug discovery applications (ex. Antibody-Drug
Post-Translational Modifications (PTM) of Tubulin
In this post, I'd like to take a look at the current understanding of tubulin PTMs, that include tyrosination/detyrosination, Δ2-tubulin formation, acetylation, phosphorylation, ubiquitination, glutamylation,
New research tools targeting PCSK9 and LDLR
There is an increasing demand for new cholesterol-lowering therapies in addition to existing treatments (e.g. targeting statins). The pharmacological inhibition of PCSK9-mediated LDLR degradation