Page 5 - Scientific Library
Fully licensed SLC cell lines for FDA and EMA recommended transporters
In a previous post, we introduced our Ready-to-use cellular models for SLC assays by GenoMembrane.
These cell lines transiently express the current FDA and EMA recommended SLC
How can TR-FRET facilitate your cell signalling studies?
Time-Resolved Förster Resonance Energy Transfer (TR-FRET) is a robust and homogeneous fluorescence detection technology and a real alternative to ELISA to perform Cell Signalling studies.
New Primary cell Models: a focus on Kidney cells
tebu-bio is pleased to announce their new partnership for a European distribution of Novabiosis, a US based manufacturer providing cryopreserved primary human cells for
World's first 3',3'-Cyclic CAMP ELISA
The cGAS-cGAMP-STING cell signalling pathway plays a critical role in antiviral and antitumor immunity as well as mediating autoimmune responses. Dysregulation or aberrant activation of
New SARS-CoV/ACE2 inhibitor assays & small molecules for drug discovery
Many initiatives led by worldwide scientific networks are currently being launched to decipher cellular mechanisms involved in SARS-CoV-2 cellular entry. For example, a recent study has
How to monitor inflammatory cytokines in anti-COVID drug discovery
The close relation between Severe Acute Respiratory Syndrome (SARS), unpaired adaptive immune responses and overexpression of inflammatory cytokines has been described more than a decade
How are mRNA vaccines changing drug discovery?
mRNA vaccines are developing very quickly with dozens of ongoing clinical trials against cancers or infectious diseases (e.g. HIV or more recently SARS-Cov-2). Recombinant monoclonal antibody (mAB) based
COVID-19: relevant cell culture models
One of the challenges in respiratory research in general, and for COVID-19 related projects in particular, is to have access to relevant in vitro cell culture models. Human lung
Immuno-Oncology: 6 must-haves to boost your projects
Alone, or in combination with other therapies, Immuno-Oncology (I-O) appears currently as one of the most promising research fields to fight cancer. Nevertheless, developing breakthrough
Reprogramming stem cells: a new innovative technology for the development of consistent and functional human cells
To overcome current cell model limitations, bit.bio have developed a new, innovative technology to reprogram human stem
Consistent, scalable human iPSC-derived glutamatergic neurons and skeletal myocytes
As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™
How can you get your mRNA ready in only a few weeks?
Synthetic mRNA is indeed the highway for today's therapeutics, whether you're working on developing new drugs against cancer targets, or whether you aim to develop new vaccines, Covid-19 being one of them.