Page 4 - Scientific Library
Bioactive neuronal lipid mediators: a focus on Synaptamide
Focus Biomolecules produces a broad range of bioactive lipid mediators as well as many small molecule inhibitors of numerous lipid metabolic pathways for use as cellular probes. These can be supplied
GPR17 and Remyelination: activators and antagonists
The absence of mature oligodendrocytes for the repair of demyelination lesions is a critical factor in the pathology of Multiple Sclerosis (MS), and other debilitating CNS disorders of myelination. As
Cell signalling: Where to find multiplex arrays for glycobiology studies
How do you detect 300 specific glycan binding proteins in one experiment? Well, in this post we'll answer this question by introducing the new Glycan Array, developed by RayBiotech for your cell signalling
Recombinant CYP Bactosomes: versatile formats for many ADME applications
Recombinant CYPs are commonly used in ADME-Tox studies as in vitro tools, mostly for reaction phenotyping, enzyme inhibition screening, clearance and metabolite ID.
"Research has shown that rCYPs expressed
Improve MS-based biomarker determination with immunocapture
During the past decade, mass spectrometry, notably LC/MS, has become a major approach to identify and quantify proteins in patient samples. It includes analysis before treatments to find the proper biomarkers
10 Human Immune Checkpoint biomarkers quantified simultaneously
Immune checkpoint molecules play an important role in T cell functionality after TCR/MHC signalling. Blockade of two B7/CD28 family checkpoint molecules, CTLA-4 and PD-1, have already demonstrated excellent
Live Cell Imaging - Watch SiR-Tubulin stained Human Osteosarcoma cells in action
As you may already know, Spirochrome have developed a broad range of Live Cell Imaging probes for the staining of DNA, Lysosome, F-Actin and Microtubules.
Based on the use of the Silicon rhodamine-like
Cardiovascular disorders: Proteomics tool for disease signature identification
Cardiovascular disease (CVD) comprehensively describes a range of pathologies of the heart and/or blood vessels. These disorders differ markedly in time-scale of development, and relative contributory
3D cell culture validation - impact of physioxic conditions on TIMP-1 expression
When compared to 2D conventional cell culture systems, experimental data obtained with 3D cell culture models have been shown in many instances to be more biologically relevant, closer to clinical conditions
Powerful and reliable solutions to decipher Actin Dynamics
As is well known, the actin cytoskeleton is a highly dynamic structure, involved in a large number of cellular processes, including muscle contraction, lamellopodial extrusion, cell locomotion, cytokinesis,
Discover the world's first Intracellular Polyamine Imaging Reagent
With their polycationic properties, polyamine organic compounds are involved in various biological functions (DNA-RNA interaction, gene expression...), and can also be considered as cancer marker.
In this
Multiplex profiling in one single blot: 15 species models to choose from
In a previous post, I introduced the C-series multiplex profiling technology from Raybiotech, a smart way to multiplex your western blot while saving time and sample volume, and decreasing the cost of