Scientific Library

Kv1.3 channels are expressed in T-cell lymphocytes and over-expressed in autoimmune diseases. They can be see as a therapeutic taget for T cell mediated autoimmune diseases.

ShK toxin (Stichodactyla helianthus

Actin binding proteins (ABPs) have a wide variety of functions in regulating the cellular function of actin. They control G-actin polymerization but also drive actin filaments severing and cross-linking

Acid-Sensing Ion Channels (ASICs) are neuronal voltage-insensitive cationic channels which are activated by extracellular protons. They belong to the ENaC/Deg superfamily of ion channels. Up to now 6

Ion channels are proteins with pore-forming abilities. Their selective capabilities to let ions cross the cell membrane involves them in crucial cellular functions (controlling membrance potential, the

Ions channels are pore-forming membrane proteins that control ion transit across the cell membrane to various stimuli. It was shown that deregulation or dysfunction of channels are clearly linked to many

To overcome current cell model limitations, bit.bio have developed a new, innovative technology to reprogram human stem cells with precise control of transcription factor expression through iPSC engineering.

As detailed in a separate post, bit.bio have developed a novel cellular reprogramming technology, opti-ox™¹ (optimized inducible overexpression), that can generate functional cells with high consistency