Scientific Library
Capping, bundling, sequestering... the role of Actin Binding Proteins
Actin binding proteins (ABPs) have a wide variety of functions in regulating the cellular function of actin. They control G-actin polymerization but also drive actin filaments severing and cross-linking
Antibiotics and microbial metabolites - revisited
What are metabolites?
Microorganisms live in a world of chemical signals. They use small molecular weight compounds, known as metabolites, to regulate their own growth and development, to encourage other
6 active compounds to rediscover rare bacterial metabolites
Microbial metabolites are a source of unequalled elements for in vitro assays. Sometimes  neglected, these active molecules naturally provide a large spectrum of structural diversity for Drug discovery
Microbial K-Ras Inhibitors
Small molecules known to modulate biological activies of the K-Ras oncogene are predominantly of synthetic origin (ex. Salirasib). Nevetheless, various publications have recently demontrated the biological
Production of eGFP mRNA Labeled with Fluorophore for Tracking of Delivery and Expression
Our Contract Research Services (CRS) team developed eGFP mRNA labeled with a fluorophore to monitor its delivery and expression efficiency in cells.
RNA Production Platform and the Associated Solutions Facilitate the Development of RNA-Based Vaccines
RNA vaccines have shown their full potential in the Covid-19 pandemic. The application of these technologies for the treatment of cancers represents a significant promise, but clinical effectiveness remains
Standardized 3D Spheroid Systems Facilitate Drug Screening and Biomarker Identification with High Relevance for Cancer Drug Discovery
Our customer needed to investigate whether modulating key culture parameters could improve the predictivity of their colorectal cancer cell-based methodology used to select CDK8 inhibitors and/or identify
Multiplex Antibody Array for Protein Profiling and Biostatistical Analysis to Assess the Effect of Oxaliplatin on Mouse Fibrosarcoma Cell Line
Oxaliplatin (OXA) is a chemotherapeutic drug which causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin is known as immunogenic cell death
Development of Cost Effective and Robust 3D Colorectal Cancer Models for Physiological Drug Response Analysis
Our customer needed to obtain in vivo like responses to drug treatment, through monitoring parameters such as gene expression, biomarker analysis, cellular viability, invasion capability.
Lipid Nanoparticles (LNP): The New Cargo for Drug Delivery
Explore how to optimize Lipid Nanoparticules (LNP) for mRNA delivery for druf development. This study highlights key formulation parameters: buffer composition, lipid selection; crucial for enhancing transfection
Unlock the Full Potential of Your Protein Production
Flexible Protein Production Services for Custom Expression & Purification
Tebubio’s Protein Production Platform offers custom expression strategies using bacterial & mammalian (HEK293) systems. Our adaptable