Page 4 - Scientific Library
How to choose the perfect buffer to get a pure, stabilised, functional protein
Protein biochemistry brings together a vast and varied world of methods of protein production, purification and characterization. Once you have successfully achieved the production of your protein in a
New - Continued use immunotherapy cell line expressing recombinant PD-1
PD-1 / NFAT Reporter - Jurkat Cell Line
The PD-1 reporter cell line is
Cell-based assays with hPBMCs for cell therapy and drug discovery
Human Peripheral Blood Mononuclear Cells (hPBMCs) are essential for designing cellular models to be used in cell therapy and drug discovery research programs [1-7, 12]. Being able to access reliable and
Pluripotent stem cells for improved reprogrammed Human Sebocytes
Following the start of our recent collaboration with Phenocell, we’re pleased to be able to provide high quality Sebocytes developed from Human induced pluripotent stem cells (iPSC). Thanks to a perfectly
How to optimise your recombinant protein purification and protein production
Undoubtedly, producing and purifying a protein is an art form.
Indeed, each recombinant protein (rec. protein) to be produced in vitro has specific characteristics and singularities, which makes its production
New Reporter cell lines for Drug discovery and Immunotherapy checkpoint research
In the last few decades, in the field of Drug Discovery, Immunotherapy has gained more and more importance for the treatment of various diseases and in particular for certain types of cancer. Based on
ELISA test to confirm elimination of Host Cell Proteins (HCP) from bioproductions
Expression systems - removing their contaminants
CHO, E. Coli and Pichia are useful expression systems for drug production. This can be for proteins, enzymes or antibody productions. Research and development
Tips and Tricks - Protein purification and production for LC-MS characterization
Mass spectrometry is a technology which is widely used in most scientific disciplines that require accurate and precise measurement of elemental and molecular components. Its use in the pharmaceutical
4 Tips to boost mRNA in vitro transcription and optimize mRNA delivery
Over the last years, mRNA-based experimental approaches have been successfully used in a broad range of research applications (genome editing, gene replacement, vaccine, immunotherapy, cellular reprogramming...)
Pluripotent Stem Cells and iPSC Research: Quality and Innovative Products
Since the discovery of reprogramming factors in 2006 and the boom of CRISPR gene editing strategies, induced pluripotent stem cells (iPSC) have emerged as new cellular models. The development of 3D cell
Therapeutic Target - Ubiquitin-Proteasome system: What about tubulin?
The ubiquitin-proteasome system (UPS) is a well-characterized protein degradation system in cells whose dysfunction is implicated in many diseases, including neurodegeneration and cancer1,2. Major UPS