Page 4 - Scientific Library
New - 4 Unique IFN Neutralizing reagents
PBL Assay Science, the specialists of Interferon related quality reagents, have just released 4 new unique products to be used in neutralization assays. I am pleased to introduce them in this post, in
How to easily screen adenosine A2AR agonists and antagonists
Recently, BPS Bioscience have released a new Adenosine A2A Receptor (A2AR / ADORA2A) Functional Recombinant Cell Line for screening A2AR agonists and antagonists. An excellent means to
Quantify ExtraCellular Matrix components - 5 popular kits you need to know
How to make Post Translational Modification characterization easier
Signal-Seeker assays (Cytoskeleton Inc.) provide researchers with the most comprehensive reagents enabling highly sensitive and specific detection of the
Cell-Based ELISA for in-cell protein phosphorylation and expression profile detection
Cell-Based ELISA tests now enable precise measurement of the phosphorylation status or expression profiles of target proteins (biomarkers) in whole cells. In this post, a review of high performing cell-based assays is made.
Interestingly, the experimental design is simple and is based on 3 steps:
- Plate
- Treat and fix your cells of interest (adherent or in suspension)
- Detect the target proteins with the optimized reagents provided in the kit (450 nm colorimetric detection)
These Colorimetric Cell-Based ELISA Kits enable the detection of various target proteins (biomarkers). Some references also enable the precise measurement of the phosphorylation status of proteins of interest. They can easily
AIM Biochips - 3D cell culture platform for Immunotherapy and T Cell therapy studies
As mentioned in a previous post the DAX Biochips from AIM Biotech are an innovative and versatile microfluidic platform, allowing researchers to more easily develop 3D cell culture
10 Human Immune Checkpoint biomarkers quantified simultaneously
Immune checkpoint molecules play an important role in T cell functionality after TCR/MHC signalling. Blockade of two B7/CD28 family checkpoint molecules, CTLA-4 and PD-1, have already demonstrated excellent
Live Cell Imaging - Watch SiR-Tubulin stained Human Osteosarcoma cells in action
As you may already know, Spirochrome have developed a broad range of Live Cell Imaging probes for the staining of DNA, Lysosome, F-Actin
HDACs: Active drug targets for Immunotherapy treatment
For many pathologies such as cancer or neurological disorders, it has been found that Histone Deacetylase (HDAC) activity is disrupted, making them promising targets for drug development.
Cancer immunotherapy: explore the cytokine "milieu" with Quantibody 200 Biomarker Service
Autologous tumour cell vaccines vs. dendritic cell vaccines: What's best, and why?
Understanding the best approach for tumour vaccinations is of growing importance in the personalized cancer immunotherapy
3D cell culture validation - impact of physioxic conditions on TIMP-1 expression
When compared to 2D conventional cell culture systems, experimental data obtained with 3D cell culture models have been shown in many instances to be more biologically relevant, closer