Page 11 - Scientific Library
Stellate cells - models for liver studies
Introduction
Hepatic stellate cells (HSC, also known as perisinusoidal cells or Ito cells), are liver-specific mesenchymal cells found in the space of Disse. HSC maintain interactions with
Main factors for different cell types...
In my previous post, we focused on 6 cytokine growth factors for cell culture. This time, we will try to find the best factor for each main cell type.
1 simple way to rapidly quantify Collagen: Sircol Collagen Assay
Collagen is a structural protein expressed in mammalian tissues (ex. skin, muscles, tendons, ligaments, cartilages, blood vessels...). Together with Elastin and Keratin, Collagen fibres give connective
Proteome, secretome, kinome… What’s it all about?
Proteome is referenced as the result of expression of the whole genome. With the recent developments of genomics, one could consider that this analysis is enough to decipher any biological mechanism...
How to select Hyaluronic Acid (HA) quantitative tests?
Hyaluronic acid (also called HA or Hyaluronan) is a glycosaminoglycan with unique characteristics. HA possesses elevated viscosity, enabling tissues (eye, skin, joint and synovial fluid...) to resist
Specific cytokines & growth factors in... angiogenesis, endothelial cells
Angiogenesis is the growth process of new blood vessels from pre-existing one's. It's a normal physiological process, observed during embryonic development. But it's also a pathological process, essentially
Secretome biomarker identification: tech tips for selecting the most suitable tools
In a previous post, I mentioned that the secretome is becoming a very hot topic in the world of
Specific cytokines & growth factors in... inflammation
Inflammation is part of the complex biological response of vascular tissues to harmful stimuli, such as pathogens, damaged cells, or irritants. Numerous cytokines are present within inflammatory
Primary cell sourcing: Cryopreserved Human Adult Sebocytes
Sebocytes are emerging cellular models to study skin biology but also to design new compounds to regulate acne, seborrhoea and other sebaceous gland-related diseases. Easy access to cryopreserved and well-qualified
Modulate hepatic inflammation
Kupffer cells are macrophages endogenous to the liver which have the ability to modulate hepatic inflammation and injury associated with various pathophysiologies and toxicities. Pro-inflammatory cytokines
Human Primary Sebocyte assay for compound testing on lipid metabolism
Sebocytes belong to the epidermal ecosystem together with hair follicules or in sebaceous glands. Sebocytes play a key role in skin health by producing sebum. These cells are now at the center of researchers'
Specific cytokines & growth factors in... hematology!
Hematology is the study of blood, blood-forming organs and blood diseases. The formation of blood cells is referred to as hematopoiesis. All cellular components of the blood are derived from hematopoietic