Page 6 - Scientific Library
Adipokines in obesity and glucose homeostasis
Obesity is the abnormal increase in adipose tissue mass. This phenomenon increases the likelyhood of a number of diseases such as heart disease, high blood pressure, type 2 diabetes, obstructive sleep
microRNAs: Keys to open cell biology’s secret chamber
As cell biologist, when working in labs I have in the past witnessed several “X-files” in a flask of cells along my way: all cells of an established cell line are supposed to have the same genetic background
Cytokines and growth factors in Angiogenesis
Angiogenesis is the growth process of new blood vessels from pre-existing one's. It's a normal physiological process, observed during embryonic development. But it's also a pathological process, essentially
microRNAs: Finding the effector - miRNA detection
Following on from my previous post in which I started to introduce a series of techniques to investigate the impact of miRNA expression on cell fate,
microRNAs: Push and observe - miRNA overexpression
In this third post of the miRNA-related series, let's take a look at miRNA overexpression.
miRNA mimics
Short RNAs are very prone to enzymatic degradation. Novel chemical technologies now
microRNAs: Inhibiting the inhibitors - Antagomirs
Following on in our series on microRNAs (miRNA - Keys to open cell biology’s secret chamber)
microRNAs: Target detection
Leading on from my previous posts (see below) exploring microRNA detection, overexpression and inhibition, this time, let's spend a moment on target detection.
miTarget databases
Antibody pairs - the rebirth of a classic
Antibody pairs have been used for years to detect biomarkers in biological samples. They are a convenient and price-wise alternative to ready-to-use ELISAs, especially when they are used on a routine basis
Focus on the Hypoxia Regulation Mechanism
The cellular and physiological effects resulting from hypoxia-dependent networks have been clearly shown to impact a number of human pathological states, including ischemic disease, diabetes, pulmonary
Tumour microenvironment - glioblastoma
Factors released by tumour cells can have an impact on the outcome of cancer in a patient, and they can be used as diagnostic or prognostic biomarkers. A deeper study on the tumour microenviroment (TME)
Gateway® cloning technology: Is it as easy as they say?
Molecular biology experts have been telling us for a while that the Gateway® cloning vectors are easy-to-use, saving them significant time and effort.
Basically, the technology allows you to start